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Managing Infection

New White Paper

Managing Wound Infections & Biofilm

A new White Paper offers a simplified yet practical summary for the management of wound infections and biofilms, based on a review of published consensus, guidance and best practice standards.

Watch the videos below for an introduction to the new White Paper.

Wound Cleansing
Mechanical debridement
Manage the gap
Use topical antimicrobial
Re-assess regularly
Why To remove non-viable tissue, debris, foreign matter, and excess exudate
When Each dressing change
How Irrigation with a force of 4-15 psi has been demonstrated as effective and safe
Why To remove and disrupt biofilms and make them more susceptible to antimicrobials1
When Each dressing change (sharp debridement as required)
How Physical disruption with gauze or pad by gentle circular motion in the wound bed
Why Gaps may lead to exudate pooling, bacterial growth, and development of biofilms5
When Each dressing change
How Dressings that conform to the wound bed or wound fillers with a secondary dressing
Why Antimicrobials such as silver have been shown to kill biofilms in vitro1
When Directly after disruption by mechanical debridement
How In particular, both silver and cadexomer iodine have been shown to kill biofilms
Why To ensure wound progression and enable change of treatment if the wound is not healing
When At every dressing change or at least once per week
How Re-assess the questions presented above
Download White Paper
The Problem
Exudate pooling could increase the risk of bacteria growth and infection, which can delay wound healing and may lead to severe complications.
The Solution

Biatain® Silicone with 3DFit Technology reduces the risk of gaps and pooling.

 

Does your current dressing match the shape of the wound?

In a large case study series, Biatain Silicone foam dressings conformed exactly to the shape and depth of 104 different wounds, creating an intimate fit, and reducing the risk of pooling and bacteria growth in the wound.4

Biatain Silicone Ag absorbs bacteria and exudate, including thicker, more viscous exudate, even under compression.

Biatain Silicone Ag sustains antimicrobial activity for up to 7 days, and disrupts, reduces and prevents regrowth of bacterial aggregates.

Significant reduction of bioburden in the wound bed

From soft tissue punch biopsies on 19 patients, Biatain Silicone Ag was shown to achieve a significant reduction of bioburden in pathogens such as S. aureus and P. aeruginosa. The case below is a 67-year-old patient with an infected diabetic foot ulcer that had been present for 8 weeks prior to treatment with Biatain Silicone Ag5

Day 1
80% sloughy tissue, moderate exudate, signs of infection Bacterial load: 4.29 log10 CFU*/g
Week 3
46% decrease in area Bacterial load: 2.4510 CFU/g
Week 6
74% decrease in area Bacterial load: 1.30 log10 CFU/g
Week 9
Complete healing
Download Evidence

The results of an in-vitro test demonstrated that Biatain Silicone Ag reduced all tested microorganisms, including antibiotic resistant strains, by more than log 4 (10,000-fold)6.

In a separate in-vitro test, a wound model from the University of Copenhagen7 was used to grow bacterial aggregates, including P. aeruginosa and S. aureus., and Biatain Silicone Ag was demonstrated to disrupt, reduce and prevent regrowth of bacterial aggregates.8

Download Evidence

References

1. Digital survey conducted by Coloplast among 1800 healthcare professionals, Spring 2018

2. World Union of Wound Healing Societies (WUWHS), Florence Congress, Position Document: Management of Biofilm, Wounds International 2016

3. Braunwarth et al., Wound depth and the need of a wound filler in chronic wounds, Wounds UK, 2017

4. Braunwarth et al., Conformability of a foam dressing – clinical experience based on 104 cases, Wounds UK, 2017

5. Lázaro-Martínez et al., Clinical and antimicrobial efficacy of a silver foam dressing with silicone adhesive in diabetic foot ulcers with mild infection, Journal of Lower Extremity Wounds, August 2019

6. Data on file, Determination of the antimicrobial effectiveness of Biatain Silicone Ag using a modified AATCC 100 test method, VV-0254113, January 2020

7. Crone et al., A novel in vitro wound biofilm model used to evaluate low frequency ultrasonic-assisted wound debridement, Journal of Wound Care, 2015

8. Christiansen et al., In vitro evaluation of a silver foam dressing with and without silicone adhesive against biofilms and a broad range of microorganisms, EWMA 2018

Thank you for your interest in Biatain® Silicone

Please fill out the form below, specifying your contact preference, and a representative will follow-up with you to discuss next steps. You must be an active healthcare professional within Canada.